The Ctrl+Alt+Del security attention sequence for logons must be enabled.
Disabling the Ctrl+Alt+Del security attention sequence can compromise system security. Because only Windows responds to the Ctrl+Alt+Del security sequence, a user can be assured that any passwords entered following that sequence are sent only to Windows. If the sequence requirement is eliminated, malicious programs can request and receive a user's Windows password. Disabling this sequence also suppresses a custom logon banner.
How this relates to the STIG checklist: STIG vs SCAP benchmark.