The system is not configured to use Safe DLL search mode.
The default search behavior, when an application calls a function in a Dynamic Link Library (DLL), is to search the current directory followed by the directories contained in the systems path environment variable. An unauthorized DLL, inserted into an applications working directory, could allow malicious code to be run on the system. Setting this policy value forces the system to search the %Systemroot% for the DLL before searching the current directory or the rest of the path.
How this relates to the STIG checklist: STIG vs SCAP benchmark.